Lyme Disease
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Borrelia burgdorferi
stain of borrelia burgdorferi

Lyme disease was named in 1977 when arthritis was observed in a cluster of children in and around Lyme, Connecticut. Other clinical symptoms and environmental conditions suggested that this was an infectious disease probably transmitted by an arthropod. Further investigation revealed that Lyme disease is caused by the bacterium, Borrelia burgdorferi. These bacteria are transmitted to humans by the bite of infected deer ticks and caused more than 23,000 infections in the United States in 2002Black-legged ticks (Ixodes scapularis) are responsible for transmitting Lyme disease bacteria to humans in the northeastern and north-central United States. On the Pacific Coast, the bacteria are transmitted to humans by the western black-legged tick (Ixodes pacificus). Ixodes ticks are much smaller than common dog and cattle ticks. In their larval and nymphal stages, they are no bigger than a pinhead. Ticks feed by inserting their mouths into the skin of a host and slowly take in blood. Ixodes ticks are most likely to transmit infection after feeding for two or more days. In the United States, Lyme disease is mostly localized to states in the northeastern, mid-Atlantic, and upper north-central regions, and to several counties in northwestern California. Individuals who live or work in residential areas surrounded by tick-infested woods or overgrown brush are at risk of getting Lyme disease. Persons who work or play in their yard, participate in recreational activities away from home such as hiking, camping, fishing and hunting, or engage in outdoor occupations, such as landscaping, brush clearing, forestry, and wildlife and parks management in endemic areas may also be at risk of getting Lyme disease

HHS Working Group on Lyme and Other Tickborne Diseases hosted webinar. Agenda is Welcome and Introduction – Dr. Ben Beard •Why we need a vaccine for Lyme disease – Dr. Stanley Plotkin •Potential vaccine strategies and targets for Lyme disease – Dr. Rich Marconi •A critical appraisal of LYMErix and lessons learned – Dr. Robert Aronowitz •Progress toward a second generation Lyme vaccine – Dr. Nina Wressnigg •Summary and conclusions – Dr. Larry Madoff
Lyme Disease 25 May 99
Recommendations of the Armed Forces Epidemiological Board (AFEB)
Lyme Disease 26 Jun 92
Recommendations of the Armed Forces Epidemiological Board (AFEB)