Questions & Answers
Adenovirus - Adenovirus Types 4 and 7 Vaccine
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Contraindications

Questions
Answers
  1. Who should NOT receive this vaccine?
    Individuals with known severe allergic reactions to any components of the vaccine; females considering pregnancy within 6 weeks of receiving the vaccine; individuals incapable of swallowing an entire tablet, whole, without chewing should not receive the vaccine.

  2. Are there any warnings or precautions associated with the vaccine?
    Yes. Vaccinees should use precaution when around children 7 years of age and younger, immunocomprised individuals and pregnant women during the 28 days following vaccination. Because the vaccine contains live adenovirus that is shed in the stool for up to 28 days following vaccination, strict hand washing and personal hygiene is required to minimize risk of transmitting or infecting others with the virus.

  3. Is pregnancy a contraindication for the adenovirus vaccine?
    Yes. The adenovirus vaccine should not be administered to pregnant females or nursing mothers.

  4. Is pregnancy testing necessary before administration of the adenovirus vaccine?
    Pregnancy testing is part of a routine serology panel for newly enlisted female recruits upon accession because pregnancy is a disqualifying condition for basic training. Do not delay vaccination pending routine recruit pregnancy testing unless pregnancy is suspected. If a female recruit has a positive HCG do not administer live vaccines including adenovirus vaccine and refer the female for follow-up per Service policy. Verbal screening for pregnancy in non-recruit populations is standard practice before administering of live vaccines.

  5. Is HIV a contraindication for the adenovirus vaccine?
    No. However, the safety and effectiveness of the Adenovirus Types 4 and 7 Vaccine, Live, Oral in immunocompromised individuals has not been evaluated. A documented negative HIV test is not required before administering live vaccines when the vaccinee is screened for immunocompromising conditions. Verbally screen individuals for HIV/AIDS, medical conditions, and/or medications that may affect the immune system before administering the adenovirus vaccine.