Questions & Answers
Smallpox - Evidence of Immunity and Vaccination - Response Interpretation
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No-Take Reaction

  1. I had a no-take reaction to my smallpox vaccination. Do I need to get another smallpox vaccination?
    An experienced healthcare provider should have determined whether you have had a successful smallpox vaccination by evaluating the vaccination site for a reaction. If this was your first vaccine in which there was no reaction, a second attempt to vaccinate should be made using a different vaccine lot and using a different vaccination site. This site may need to be checked more carefully and more often for a take reaction.

    If after your second smallpox vaccination there is still no evidence of a take reaction, you are considered immune to smallpox for military-related requirements, including deployment. Please contact the IHB if you have additional questions or concerns.